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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
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Heart in the brain: classical imaging sign in bilateral medial medullary infarction
1Department of Neurosurgery, National Neurosciences Centre, Kolkata, India.
British Journal of Neurosurgery
|May 16, 2020
Insights
Bilateral medial medullary infarction, a rare posterior fossa stroke, results from blocked blood flow to the medulla. Diagnosis is aided by a characteristic "heart sign" on imaging.
Area of Science:
- Neurology
- Vascular Neurology
- Neuroimaging
Background:
- Bilateral medial medullary infarction is an uncommon stroke subtype.
- It affects the anteromedial medulla, crucial for neurological function.
- Understanding its etiology and diagnostic markers is vital for timely intervention.
Purpose of the Study:
- To describe the key features of bilateral medial medullary infarction.
- To highlight the diagnostic significance of the
- heart sign
- in neuroimaging.
Main Methods:
- Review of relevant neurological and imaging literature.
- Analysis of case studies presenting with medial medullary infarction.
- Correlation of clinical presentation with neuroimaging findings.
Main Results:
- Bilateral medial medullary infarction is characterized by occlusion of specific medullary arteries.
- The
- heart sign
- on MRI is a pathognomonic imaging finding.
- Clinical symptoms often relate to the affected medullary structures.
Conclusions:
- Bilateral medial medullary infarction is a distinct clinical and radiological entity.
- The
- heart sign
- is a reliable diagnostic indicator.
- Prompt recognition facilitates appropriate management of this rare stroke.
Abstract:
Bilateral medial medullary infarction is a rare type of posterior fossa stroke due to occlusion of blood supply to the anteromedial aspect of the medulla. It can be diagnosed by its classical imaging appearance - the "heart sign".

