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Left Atrial High-grade Sarcoma With Focal Osteosarcomatous Differentiation
Jessica Napuri1, Jose Paz1, Pedro Valdes2
1Internal Medicine, Palmetto General Hospital, Hialeah, USA.
Cureus
|May 16, 2020
Summary
This case report details an extremely rare cardiac synovial sarcoma in an 85-year-old female. Early diagnosis and surgical intervention are crucial for managing this rare malignant cardiac tumor.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Malignant cardiac tumors are rare, with sarcomas being exceptionally uncommon and lacking established management guidelines.
- Primary cardiac sarcomas represent a small fraction of all primary cardiac tumors.
Observation:
- An 85-year-old female presented with shortness of breath and chest pain, found to have a 4 cm left atrial mass via imaging.
- The mass, suspicious for malignancy, was surgically debulked.
- Histopathology revealed a high-grade sarcoma with focal osteosarcomatous differentiation, identified as a cardiac synovial sarcoma.
Findings:
- Cardiac synovial sarcomas are exceedingly rare, accounting for less than 0.1% of primary cardiac tumors.
- This case represents one of fewer than seven reported instances of cardiac synovial sarcoma in the literature.
- The patient's tumor exhibited spindle cell morphology with bone and cartilage formation.
Implications:
- Reporting rare cases like this cardiac synovial sarcoma is vital for advancing medical knowledge due to limited literature.
- Further research and case follow-ups are necessary to understand the behavior and optimal management of this rare condition.
- Highlights the importance of comprehensive histopathological evaluation for diagnosing rare cardiac neoplasms.
