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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
The year in review: advances in interventional cardiology in 2019
Keyvan Karimi Galougahi1,2,3, Gregory Petrossian4, Gregg W Stone4,5
1Department of Cardiology, Royal Prince Alfred Hospital and University of Sydney.
Insights
Major studies in 2019 advanced interventional cardiology, showing pharmaco-invasive management is key for coronary artery disease. Revascularization improves quality of life and angina relief in stable ischemic heart disease.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Clinical Practice Guidelines
Background:
- Recent advancements in interventional cardiology have significantly impacted evidence-based knowledge.
- Key areas include stable ischemic heart disease (SIHD), acute coronary syndromes, and interventional devices.
Purpose of the Study:
- To review major studies from 2019 in interventional cardiology.
- To highlight findings on pharmaco-invasive management of coronary artery disease.
- To summarize the impact of these trials on clinical practice.
Main Methods:
- Review of recent randomized studies in interventional cardiology.
- Analysis of trials focusing on revascularization versus medical treatment.
- Evaluation of data on interventional devices, pharmacotherapy, and intravascular guidance.
Main Results:
- SIHD patients with moderate ischemia have similar event-free survival with conservative or invasive strategies.
- Revascularization significantly improves quality of life and reduces angina in SIHD.
- Percutaneous coronary intervention (PCI) and coronary artery bypass grafting show similar 5-year outcomes for left main coronary artery disease.
- Conservative management is as effective as invasive approach for out-of-hospital cardiac arrest without ongoing ischemia.
- Staged complete revascularization benefits ST-segment elevation myocardial infarction patients with multivessel disease.
- P2Y12 inhibitor monotherapy is safe and effective for post-PCI atrial fibrillation patients on anticoagulation.
- Intravascular imaging guidance improves post-PCI outcomes.
Conclusions:
- Pharmaco-invasive strategies are crucial in managing coronary artery disease.
- Revascularization offers significant benefits in quality of life and symptom relief for SIHD patients.
- Intravascular imaging should be increasingly utilized to improve post-PCI outcomes.
Purpose Of Review:
Major studies in interventional cardiology in 2019 have added substantial new evidence for pharmaco-invasive management of coronary artery disease. The review highlights the main findings of a selection of these trials and summarizes their impact on clinical practice.
Recent Findings:
Recent randomized studies examining the efficacy of revascularization or medical treatment in stable ischemic heart disease (SIHD), treatment of acute coronary syndromes, emerging interventional devices, adjunctive pharmacotherapy, and intravascular imaging and physiology guidance have substantially advanced the evidenced-based knowledge in interventional cardiology.
Summary:
Patients with SIHD and at least moderate myocardial ischemia have similar event-free survival after an initial conservative strategy of optimal medical therapy versus an upfront invasive strategy. Quality of life and angina-free status are significantly improved with revascularization. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting provide similar 5-year outcomes in patients with left main coronary artery disease and low or intermediate disease complexity. An initially conservative management is equally effective as an early invasive approach in patients with out-of-hospital cardiac arrest without ongoing ischemia. Patients with ST-segment elevation myocardial infarction and multivessel disease benefit from staged complete revascularization after primary PCI. Post-PCI, patients with atrial fibrillation requiring anticoagulation can safely and effectively be treated with P2Y12 inhibitor monotherapy without aspirin. Lastly, intravascular imaging guidance improves post-PCI outcomes, warranting increased use in clinical practice.
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