Related Experiment Video
Updated: Dec 21, 2025

Author Spotlight: Advancing Biopsy Techniques with Transesophageal Ultrasound
Published on: November 21, 2023
Office-Based Lower Airway Endoscopy: Feasibility and Safety
Eulalia Amador1, William S Tierney1, Brandon Hopkins1
1Cleveland Clinic Foundation, Cleveland, Ohio, U.S.A.
Office-based lower airway endoscopy (OLAE) is a safe procedure for pediatric patients, even those with comorbidities. While slightly more challenging than previously thought, OLAE offers a safe alternative to operative laryngoscopy.
Area of Science:
- Pediatric Pulmonology
- Otolaryngology
- Flexible Endoscopy
Background:
- Office-based lower airway endoscopy (OLAE) is an emerging procedure for evaluating pediatric airway conditions.
- Assessing the ease and safety of OLAE in patients with and without comorbidities is crucial for its widespread adoption.
Purpose of the Study:
- To determine the ease and safety of office-based lower airway endoscopy (OLAE).
- To identify common indications and diagnoses associated with OLAE.
- To evaluate OLAE in pediatric patients with and without comorbidities.
Main Methods:
- Retrospective review of 706 in-office flexible fiberoptic procedures in 567 patients.
- Utilized a grading system to assess visualization of the subglottis, trachea, and carina.
- Analyzed 488 videos, with 105 OLAE procedures included for detailed review.
Main Results:
- Laryngomalacia was the most frequent diagnosis (36%) in OLAE procedures.
- Tracheal visualization showed statistical significance between different types of laryngomalacia (P=.035).
- No complications were identified in any of the OLAE procedures, including those with comorbidities.
Conclusions:
- Office-based lower airway endoscopy (OLAE) is a safe alternative to operative laryngoscopy in pediatric patients.
- OLAE may be more challenging than previously reported, particularly in combined laryngomalacia types.
- The procedure appears safe for patients with comorbidities when appropriate precautions are implemented.
Related Concept Videos
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures III: Video Capsule Endoscopy
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Endoscopic Procedures V: ERCP
Patient...

