[Clinical evaluation of S 6472 granule preparation (sustained-release cefaclor) in chronic bronchitis]

The S 6472 granule preparation (sustained-release cefaclor preparation) was administered to 15 cases of chronic bronchitis for its clinical evaluation; a daily dosage of 750 mg was orally given in 2 divided doses after breakfast and dinner for a duration of 7 to 22 days. Clinical effects were good in 11 cases, fair in 1 case and poor in 3 cases. Among the 13 cases other than 2 unadaptable Pseudomonas infections, good effectiveness was found in 11 cases (efficacy rate: 84.6%). There appeared to be no side effects or abnormal laboratory test values due to administration of this drug.