Related Experiment Video
Updated: Dec 21, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Development on Health Risk Assessment Method for Multi-Media Exposure of Hazardous Chemical by Chemical Accident
Hyong Jin Hong1, Si Hyun Park1, Hui Been Lim1
1Department of Nano and Biological Engineering, Seo-Kyeong University, 124, Seogyeong-ro, Seongbuk-gu, Seoul 02713, Korea.
Abstract:
In this study, a long-term health risk assessment was conducted for complex, multimedia exposure where the exposure duration was set for the leak of a hazardous chemical spilled after an accident. The study designed a virtual chemical accident scenario where 40 tons of benzyl chloride leaked in a factory inside the Ulsan Petrochemical Industrial Complex for one hour on 1 January 2017. Using a multimedia environmental dynamics model, benzyl chloride concentrations in air and soil were estimated. The time when the atmospheric concentration was less than or equal to the background concentration was recorded as the end point. An assessment of the cancer risk via soil ingestion was carried out after dividing the subjects into four age groups (0-9 years; 10-18 years; 19-65 years; >65 years). All age groups showed an increased cancer risk where the values exceeded 1.0 × 10-6. The 0-9 years age group showed the largest distribution (4.27% of the total area) with the highest maximum and mean values. The distribution maps for all age groups exhibited a trend towards the southeast of the accident site.
More Related Videos
08:23An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
Published on: December 25, 2021
10:10Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
Published on: February 23, 2020
Related Concept Videos
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Hazard Ratio
For example, in a clinical trial...
Mutagenicity and Carcinogenicity
Hazard Rate
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...