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Dual-Purpose Photometric-Conductivity Detector for Simultaneous and Sequential Measurements in Flow Analysis
Thitirat Mantim1,2,3, Korbua Chaisiwamongkhol1,4,5, Kanchana Uraisin1,3
1Flow Innovation-Research for Science and Technology Laboratories (FIRST Labs), Bangkok 10400, Thailand.
Molecules (Basel, Switzerland)
|May 17, 2020
Summary
A novel dual-purpose detector combines photometric and conductivity measurements for flow analysis. This system enables simultaneous detection of dyes and salts, and sequential analysis of creatinine and urine conductivity.
Area of Science:
- Analytical Chemistry
- Instrumental Analysis
Background:
- Flow-based analysis requires versatile detection systems.
- Simultaneous or sequential measurements enhance analytical efficiency.
Purpose of the Study:
- To develop and evaluate a dual-purpose detector for simultaneous photometric and conductivity measurements.
- To integrate this detector with a sequential injection analysis (SIA) system.
Main Methods:
- A paired emitter-detector diode (PEDD) for photometry and a capacitively coupled contactless conductivity detector (C4D) were employed.
- A Z-configuration flow cell with integrated PEDD and C4D electrodes was designed.
- The system was tested for simultaneous detection of dye absorbance and salt conductivity, and sequential analysis of creatinine and urine conductivity.
Main Results:
- The dual-purpose detector successfully performed simultaneous photometric and conductivity measurements.
- Sequential analysis of creatinine and urine conductivity was achieved using the developed system.
- The detector demonstrated utility in analyzing both model solutions and real biological samples (urine).
Conclusions:
- The developed dual-purpose detector offers a versatile platform for flow-based analytical applications.
- Integration with SIA allows for efficient simultaneous and sequential measurements.
- This technology has potential applications in various fields requiring combined photometric and conductivity analysis.
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