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Injectable Biomaterials for Dental Tissue Regeneration.
Håvard Jostein Haugen1, Poulami Basu1, Mousumi Sukul1
1Department of Biomaterials, Institute of Clinical Dentistry, Faculty of Odontology, University of Oslo, 0317 Oslo, Norway.
International Journal of Molecular Sciences
|May 17, 2020
Summary
Injectable biomaterial scaffolds are crucial for dental tissue regeneration, especially for hard-to-reach oral defects. Nanofiber technology shows promise for restoring both the function and biological purpose of dental tissues.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Dental Engineering
Background:
- Injectable scaffolds offer advantages over pre-formed ones for dental tissue regeneration.
- Maxillofacial defects are often small, confined, and difficult to access, necessitating minimally invasive solutions.
- Biomaterials are essential for developing effective tissue engineering strategies in dentistry.
Purpose of the Study:
- To review different types of biomaterials used in dental tissue regeneration.
- To explore the potential application of nanofibers in regenerating dental tissues.
- To highlight the role of injectable biomaterials in restoring dental tissue function and biology.
Main Methods:
- Narrative review of existing literature on biomaterials for dental regeneration.
- Analysis of studies focusing on injectable scaffolds and nanofiber technologies.
- Discussion of the clinical applicability of these materials in dentistry.
Main Results:
- Injectable biomaterials are highly suitable for dental applications, particularly for small or inaccessible defects.
- Nanofibers present a promising avenue for dental tissue engineering.
- Tissue engineering with injectable biomaterials can restore both functional and biological aspects of dental tissues.
Conclusions:
- Injectable biomaterial scaffolds are pivotal for advancing dental tissue regeneration.
- Nanofiber-based approaches hold significant potential for future dental tissue engineering applications.
- Tissue engineering strategies utilizing injectable biomaterials offer a viable path to restoring complex dental defects.

