Assisted reproduction trends in Czech Republic National Assisted Reproduction Register 2007-2017

Area of Science:

• Reproductive Medicine
• Public Health
• Epidemiology

Background:

• Assisted reproduction (AR) is crucial for managing infertility.
• Understanding national trends in AR is vital for healthcare planning and policy.
• The Czech Republic has a well-established National Assisted Reproduction Register (NRAR).

Purpose of the Study:

• To analyze trends in assisted reproduction (AR) in the Czech Republic between 2007 and 2017.
• To identify key performance indicators and demographic factors influencing AR in the Czech Republic.
• To evaluate the effectiveness of AR treatments and national policies.

Main Methods:

• Retrospective national epidemiologic study.
• Analysis of data from the Czech Republic National Assisted Reproduction Register (NRAR) spanning 2007-2017.
• Inclusion of data from the Department of Obstetric and Gynecology, Charles University, Prague.

Main Results:

• A consistent increase in AR cycles and centers was observed, reaching 42,773 cycles and 43 centers by 2017.
• Egg Donation and Oocyte Receipt cycles formed significant components of AR treatments.
• Intracytoplasmic sperm injection (ICSI) dominated fertilization methods (96% in 2017), while embryo transfers were reduced (average 1.18 in 2017 for women ≤35 years) to minimize multiple pregnancies.
• Female age over 32 was identified as a critical factor impacting fertility and AR outcomes.

Conclusions:

• The Czech National Assisted Reproduction Register (NRAR) is a valuable resource for detailed AR treatment information.
• Data from NRAR supports informed decision-making for the Ministry of Health, health insurances, clinicians, and patients.
• The register facilitates continuous quality improvement and strategic planning in assisted reproduction services.