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Updated: Sep 21, 2026

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
12:15

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Update on cerebral hyperperfusion syndrome

Yen-Heng Lin1, Hon-Man Liu2,3

  • 1Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan.

Journal of Neurointerventional Surgery
|May 17, 2020
PubMed

Insights

Cerebral hyperperfusion syndrome (CHS) is a post-procedure complication. This review details CHS epidemiology, diagnosis, and management, emphasizing uncertainties in neurointerventional surgery.

Area of Science:

  • Neurology
  • Neurosurgery
  • Vascular Medicine

Background:

  • Neurointerventional surgery is standard for cerebral vessel stenosis/occlusion.
  • Endovascular thrombectomy is crucial for acute ischemic stroke.
  • Cerebral hyperperfusion syndrome (CHS) is a clinical event post-revascularization.

Purpose of the Study:

  • To review recent studies on CHS epidemiology, diagnosis, and management.
  • To identify uncertainties in CHS understanding and treatment.
  • To consider CHS in both acute and chronic cerebrovascular conditions.

Main Methods:

  • Literature review of recent studies on CHS.
  • Analysis of data predominantly from carotid angioplasty and stenting studies.
  • Discussion of diagnostic criteria and hemodynamic assessment using imaging.

Main Results:

  • CHS definition and diagnostic criteria are diverse.
  • Impaired cerebrovascular autoregulation is key, but mechanisms are unclear.
  • Clinical presentation and risk factors vary; diagnosis post-thrombectomy is complex, requiring consideration of reperfusion injury.

Conclusions:

  • Further research is needed to clarify CHS pathophysiology and standardize diagnosis.
  • Hemodynamic assessment aids pre-procedural patient selection.
  • Management includes intensive blood pressure control and staged angioplasty.

Keywords:
complicationhemorrhagestentstroke

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