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Murine Renal Transplantation Procedure
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Coronavirus disease 2019 in renal transplant recipients: Report of two cases

Dongrui Cheng1,2, Jiqiu Wen1,2, Zhengzhao Liu1,2

  • 1Department of Nephrology, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University, Nanjing, China.

Transplant Infectious Disease : an Official Journal of the Transplantation Society
|May 17, 2020
PubMed

Insights

This study reports two successful Coronavirus disease 2019 (COVID-19) cases in renal transplant recipients. Management involved stopping immunosuppressants and using low-dose methylprednisolone, preventing rejection.

Area of Science:

  • Nephrology
  • Transplantation
  • Infectious Diseases

Background:

  • Limited data exists on Coronavirus disease 2019 (COVID-19) management in renal transplant recipients.
  • Renal transplant recipients are a vulnerable population during the COVID-19 pandemic.

Observation:

  • Two renal transplant recipients presented with COVID-19.
  • Treatment involved discontinuing immunosuppressants and initiating low-dose methylprednisolone therapy.

Findings:

  • Both patients recovered and were discharged without signs of organ rejection.
  • The treatment regimen was effective in managing COVID-19 in these patients.

Implications:

  • This case series offers valuable insights into managing COVID-19 in renal transplant recipients.
  • The findings suggest a potential treatment protocol for similar cases, emphasizing immunosuppressant modification and corticosteroid therapy.

Keywords:
COVID-19SARS-CoV-2immunosuppressantmethylprednisolonerenal transplant recipient

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