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Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms
Published on: May 10, 2024
Outcomes of young children hospitalized with acute wheezing
Sasawan Chinratanapisit1, Paskorn Sritipsukho2,3, Araya Satdhabudha4
1Department of Pediatrics, Bhumibol Adulyadej Hospital, Thailand.
Insights
Recurrent wheezing in children is linked to being the second-born or more, vitamin D insufficiency, a history of wheezing, and allergic rhinitis. These factors increase the risk of emergency visits and hospitalizations within a year.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Nutritional Epidemiology
Background:
- Wheezing is a prevalent symptom in preschool-aged children.
- Identifying risk factors for recurrent wheezing is crucial for effective management and prevention strategies.
Purpose of the Study:
- To determine the incidence of recurrent wheezing in young children hospitalized with acute wheezing.
- To explore factors associated with recurrent wheezing within 12 months post-hospitalization.
Main Methods:
- A longitudinal study involving 236 children (6 months to 5 years) hospitalized for acute wheezing in Thailand.
- Data collected included demographics, home environment, clinical characteristics, serum specific IgE levels, and serum 25-hydroxyvitamin D (25OHD) concentrations.
- Follow-up for 12 months assessed recurrent wheezing events, emergency visits, and hospitalizations.
Main Results:
- Of 236 children, 39.8% experienced their first wheezing episode. Atopy was present in 83.5% and vitamin D insufficiency in 23.7%.
- The one-year risk of emergency visits for recurrent wheezing was 49.7%, and hospitalization risk was 23.1%.
- Multivariable analysis identified being the second-born or more (aOR 2.5), vitamin D insufficiency (aOR 2.3), prior wheezing history (aOR 1.9), and allergic rhinitis (aOR 1.6) as significant risk factors.
Conclusions:
- Being the second-born or more, vitamin D insufficiency, a history of wheezing, and allergic rhinitis are significant risk factors for recurrent wheezing in young children.
- These findings highlight the importance of addressing vitamin D levels and managing allergic conditions in children prone to wheezing.
Background:
Wheezing in preschool children is a common symptom.
Objective:
The study aimed to determine an incidence of recurrent wheezing among young children who had been hospitalized with acute wheezing after 12 months. Factors associated with recurrent wheezing were explored.
Methods:
A longitudinal study was conducted among 236 children, aged between 6 months and 5 years, who were hospitalized with acute wheezing in 4 hospitals located in Bangkok and adjacent provinces, Thailand. Demographics, house environments and clinical characteristic data were collected at entry. Serum specific IgE levels against common food and inhalant allergens and serum 25-hydroxyvitamin D (25OHD) concentrations were measured.
Results:
At entry, the mean age was 24.4 months (SD = 15.7 months). Of 236 hospitalized children with acute wheezing, ninety-four cases (39.8%) were the first wheezing episode of life. By laboratory results, 197 (83.5%) and 56 (23.7%) children were atopic and had vitamin D insufficiency respectively. There were 195 cases completely followed for 12 months. One-year risk of emergency visits and hospitalization due to recurrent wheezing were 49.7% and 23.1% respectively. By multivariable analysis, being the second born child or more, vitamin D insufficiency, "ever wheeze", and allergic rhinitis were significantly associated with recurrent wheezing within 12 months with adjusted odds ratios of 2.5 (95% confidence interval: 1.3-5.3), 2.3 (95% confidence interval: 1.1-4.4), 1.9 (95% confidence interval: 1.2-3.5), and 1.6 (95% confidence interval: 1.3-2.9) respectively.
Conclusions:
Being the second born child or more, vitamin D insufficiency, ever wheeze, and allergic rhinitis were significant risks of recurrent wheezing.
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