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[Effect of activities profile variations on health-related quality of life among breast cancer patients: Secondary
Eric Reynes1, Sophie E Berthouze2, Aude-Marie Foucaut3
1Université Lyon, université Claude-Bernard Lyon 1, laboratoire sur les vulnérabilités et l'innovation dans le sport (L-ViS, EA 7428), 69622 Lyon, France; UFR STAPS, 27-29, boulevard du 11 Novembre 1918, 69622 Villeurbanne cedex, France.
Introduction:
Lifestyle changes in breast cancer patients, by physical activity increasing, are becoming a main objective in supportive care. The objective of this study was to explore the impact of the daily activity profile evolution on the quality of life among this public.
Methods:
Sixty patients (18 to 75 years) with non-metastatic breast cancer were randomized to a 2:1 ratio (physical activity intervention; control) in the PASAPAS randomized clinical trial. Multiple linear regression analyzes were computed to explain quality of life scores 6 months after the start of adjuvant therapy. Variables retained were the baseline quality of life scores, the anxiety trait, the randomization arm, the variations of time spent in different physical activity classes ([3-4 [MET, [4-6 [MET, ≥6 MET) and in sedentary behaviors.
Results:
Only the decrease in time spent in sedentary behaviors really appeared as a predictor of the quality of physical life. Participation in the intervention group appeared as a predictor of quality of mental life.
Discussion:
Results plead in favor of sedentary life style decrease as part of the objectives of care program for women with breast cancer. It also highlights the need of collective supervised sessions implemented by competent staff. This research also suggests that the dynamics of daily activity profile variations should be studied further in association to quality of life.
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