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Marine-derived Polyaromatic Butenolides - Isolation, Synthesis and Biological Evaluations

Joe Bracegirdle1, Robert A Keyzers1

  • 1School of Chemical and Physical Sciences, and Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.

Current Pharmaceutical Design
|May 19, 2020
PubMed

Keywords:
Marine natural productsantibioticscadiolidesprunolidesrubrolidessynthesis

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Aromatic Compounds: Overview01:25

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In general, the term ‘aromatic’ indicates a pleasant smell or fragrance from fresh flowers, freshly prepared coffee, etc. In the early history of organic chemistry, many benzene derivatives were isolated from the pleasant odor oils of the plants. For example, vanillin was isolated from the oil of vanilla, methyl salicylate from the oil of wintergreen, and cinnamaldehyde from the oil of cinnamon. They all had a pleasant odor; hence the name aromatic was given.
In 1825, Faraday isolated benzene...