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Updated: Dec 21, 2025

Identification and Dissection of Diverse Mouse Adipose Depots

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

Sex Differences in Adipose Tissue Function.

Kathleen M Gavin¹, Daniel H Bessesen²

¹Division of Geriatric Medicine, Department of Medicine, Eastern Colorado VA Geriatric, Research, Education, and Clinical Center (GRECC), University of Colorado Anschutz Medical Campus, 12631 East 17th Avenue, Aurora, CO 80045, USA.

Endocrinology and Metabolism Clinics of North America

|May 19, 2020

Summary

This summary is machine-generated.

Sex steroids influence how men and women store fat and release hormones. Understanding these sex-based differences in adipose tissue is key for personalized disease prevention and weight management strategies.

Keywords:

Estrogen Hormone action Hormone replacement therapy Regional adiposity Sex differences Testosterone

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Localization, Identification, and Excision of Murine Adipose Depots

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

Area of Science:

Endocrinology
Metabolism
Sex Differences in Physiology

Background:

Regional adipose tissue distribution shows significant variation between sexes.
Sex steroids play a crucial role in regulating adipose tissue accumulation and secretory functions.
These hormonal influences are mediated through diverse direct and indirect mechanisms.

Purpose of the Study:

To explore the sex-based differences in adipose tissue function.
To understand the role of sex steroids in modulating metabolism and nutrient homeostasis.
To identify potential targets for tailored disease prevention and treatment strategies.

Main Methods:

Review of existing literature on sex steroids and adipose tissue.
Analysis of mechanisms controlling adipose tissue metabolism in males and females.
Comparative study of hormonal regulation of nutrient homeostasis.

Main Results:

Adipose tissue distribution and function are distinctly regulated by sex steroids in males and females.
Sex steroids tailor metabolic processes to meet the specific physiological needs of each sex.
Variations in adipose tissue function contribute to sex-specific differences in nutrient homeostasis and body weight regulation.

Conclusions:

A comprehensive understanding of sex-based adipose tissue differences is essential.
This knowledge can inform the development of sex-specific strategies for disease prevention and treatment.
Insights into these differences offer fundamental understanding of nutrient homeostasis and body weight regulation.