Sex Differences in Adipose Tissue Function
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Updated: Dec 21, 2025

Identification and Dissection of Diverse Mouse Adipose Depots
Published on: July 11, 2019
Kathleen M Gavin1, Daniel H Bessesen2
1Division of Geriatric Medicine, Department of Medicine, Eastern Colorado VA Geriatric, Research, Education, and Clinical Center (GRECC), University of Colorado Anschutz Medical Campus, 12631 East 17th Avenue, Aurora, CO 80045, USA.
Abstract:
Regional adipose tissue distribution differs between men and women. Differences in the accumulation of adipose tissue as well as the regulation of secretion of a number of products from adipose tissue are under the control of sex steroids, which act through a wide variety of mechanisms, both direct and indirect, to tailor metabolism to the unique needs of each sex. A fuller understanding of sex-based differences in adipose tissue function may help with tailored strategies for disease prevention and treatment and provide insights into fundamental differences in the processes that regulate nutrient homeostasis and body weight.
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