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Vaccine Hesitancy and Low Immunization Rates in Children with Down Syndrome.

Diane L Langkamp1, Anna Dusseau1, Miraides F Brown2

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Parental vaccine hesitancy is a concern for children with Down syndrome. The Parent Attitudes about Childhood Vaccines Survey (PACV) can identify hesitant parents, highlighting the need for improved vaccination rates in this population.

Keywords:
Down syndromeimmunizationsvaccine hesitancy

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Area of Science:

  • Pediatric Health
  • Vaccinology
  • Public Health

Background:

  • Vaccine hesitancy and refusal pose challenges to achieving herd immunity.
  • Children with Down syndrome may have unique considerations regarding vaccination schedules and adherence.

Purpose of the Study:

  • To assess the prevalence of vaccine hesitancy and refusal in parents of children with Down syndrome.
  • To evaluate the association between the Parent Attitudes about Childhood Vaccines Survey (PACV) scores and actual vaccine receipt in this cohort.

Main Methods:

  • The PACV was mailed to parents of children with Down syndrome attending a specialized clinic.
  • Survey responses were linked to immunization records to assess vaccination status at 19 months of age.

Main Results:

  • A 52% response rate was achieved, with 60 surveys linked to vaccination records.
  • PACV scores significantly correlated with delays in immunization.
  • Parents who refused all vaccines had PACV scores of 50 or higher.
  • Only 58% of children with Down syndrome were up-to-date on the 7-vaccine series at 19 months.

Conclusions:

  • The PACV appears to be a useful tool for identifying vaccine-hesitant parents of children with Down syndrome.
  • Increased emphasis on timely vaccination is crucial for optimizing the health of children with Down syndrome and preventing hospitalizations.