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Updated: Dec 21, 2025
P300-Based Brain-Computer Interface Speller Performance Estimation with Classifier-Based Latency Estimation
Published on: September 8, 2023
Habituation of P300 in the Use of P300-based Brain-Computer Interface Spellers: Individuals With Amyotrophic Lateral
Xiaoqian Yu1, Leandro da Silva-Sauer1,2, Emanuel Donchin1
1Department of Psychology, 7831University of South Florida, Tampa, FL, USA.
Abstract:
The P300-based brain-computer interface speller can provide motor independent communication to individuals with amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disorder that affects the motor system. P300 amplitude stability is critical for operation of the P300 speller. The P300 has good long-term stability, but to our knowledge, short-term habituation in the P300 speller has not been studied. In the current study, 15 participants: 8 ALS patients and 7 age-matched healthy volunteers (HVs), used 2 versions of P300 spellers, Face speller and Flash speller, each for 30 minutes. The ALS group performed as well as the HVs in both spellers and HVs did better with the Face speller than Flash speller while the ALS group performed equally well in both spellers. Neither intra-run P300 habituation nor inter-run P300 habituation was found. The P300 speller could be a reliable communication device for individuals with ALS.
