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Updated: Dec 21, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Why do we need cohort studies?
1Women's Health Research Program, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Abstract:
Cohort studies play an important role in medical research but it is important to understand their limitations. Some large ongoing cohort studies continue to provide critical insights into the causes of chronic disease. Confounding is a major challenge but can be dealt with during both the design and analysis phases of a cohort study. Planning for inclusion of potential confounders in the analysis should be part of the study protocol. The STROBE guidelines have improved the performance and reporting of cohort studies.
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