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Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging
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Published on: June 29, 2013

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New Innovations and Devices in the Management of Chronic Limb-Threatening Ischemia

Tanner I Kim1, Peter A Schneider2

  • 1Division of Vascular Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.

Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists
|May 19, 2020
PubMed

Insights

Chronic limb-threatening ischemia (CLTI) management requires new solutions. This review explores advancements and novel devices for effective CLTI treatment, focusing on endovascular revascularization techniques.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Regenerative Medicine

Background:

  • Growing prevalence of chronic limb-threatening ischemia (CLTI) necessitates advanced treatment strategies.
  • Current CLTI diagnosis is primarily clinical, with balloon-based endovascular revascularization being the predominant approach.
  • Existing treatments face limitations in durability and effectiveness for CLTI patients.

Purpose of the Study:

  • To review and categorize recent advancements in CLTI management.
  • To highlight innovative techniques and technologies for CLTI treatment.
  • To provide an outlook on novel devices currently under investigation for CLTI.

Main Methods:

  • Systematic literature review of recent developments in CLTI management.
  • Categorization of innovative endovascular techniques and devices.
  • Analysis of emerging technologies for CLTI treatment.

Main Results:

  • Identification of multiple innovative techniques and technologies in development or early use for CLTI.
  • Overview of recent progress in the clinical management of CLTI.
  • Highlighting of promising novel devices for future CLTI interventions.

Conclusions:

  • Significant advancements are being made in CLTI treatment options.
  • Novel devices and techniques show promise for improving durable outcomes in CLTI.
  • Continued research and development are crucial for addressing the growing CLTI patient population.

Keywords:
angioplastybelow-the-knee arteriesbioabsorbable scaffoldschronic limb-threatening ischemiadissectionsdrug deliverydrug-coated balloondrug-eluting stentendovascular therapyfemoropopliteal segmentintravascular lithoplastypercutaneous deep venous arterializationretrograde pedal accessserrated balloonstent

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