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A retrospective analysis of risk factors associated with catheter-related thrombosis: a single-center study
Xuezhen Zhou1, Xi Lin2, Runnan Shen2
1Department of Nursing, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Insights
Identifying risk factors for catheter-related thrombosis is crucial. Malignancy, prior catheterization, thrombophilia history, recent surgery, and longer catheter duration increase risk, while anticoagulation is protective.
Area of Science:
- Medical research
- Vascular medicine
- Patient safety
Background:
- Catheter-related thrombosis (CRT) can lead to serious complications like infections, deep venous thrombosis, and pulmonary embolism.
- Understanding CRT risk factors is vital for developing effective catheter care guidelines.
Purpose of the Study:
- To identify significant risk factors associated with catheter-related thrombosis in patients undergoing venous catheterization.
Main Methods:
- A retrospective study analyzed data from 1,532 patients who underwent venous catheterization.
- Logistic regression, chi-squared, Fisher's exact, and t-tests were used to evaluate patient characteristics, catheter factors, and care practices.
Main Results:
- Twenty-eight patients developed intraductal thrombi.
- Significant risk factors for CRT included malignancy, prior catheterization, thrombophilia history, recent surgery, and catheterization duration (p < 0.05).
- Catheter brand, lumen number, insertion direction, and care factors were not significantly associated with CRT.
Conclusions:
- Malignancy, history of thrombophilia, prior catheterization, recent surgery, and catheterization duration are key risk factors for CRT.
- Prophylactic anticoagulation demonstrated effectiveness in preventing and treating CRT.
Background:
Catheter-related thrombosis may lead to catheter infections and failure, further deep venous thrombosis, and pulmonary embolism. Recognizing the risk factors for catheter-related thrombosis is extremely important to inform the development of catheter care guidelines.
Methods:
Data were collected from a total of 1,532 patients who had undergone venous catheterization, including indwelling catheterization from 19 March 2019 to 30 March 2019 in the Sun Yat-sen Memorial Hospital. The factors for which data were to be collected included the patients' physical characteristics, catheter-related factors, and catheter care-related factors. Logistic regression analysis, the chi-squared test, Fisher's exact test, and the t-test were used to analyze the data.
Results:
Of the 1,532 patients studied, 28 developed intraductal thrombi, and of the factors analyzed, malignancy, a catheterization history, a history of thrombophilia, surgery during the week before catheterization, the catheterization duration, and anticoagulant therapy were significant risk factors associated with catheter-related thrombosis (all p < 0.05). There were no significant associations between the catheter brand, the number of lumens, the insertion direction, or the factors associated with catheter care and catheter-related thrombosis (all p > 0.05).
Conclusion:
Our study incorporated clear and systematic risk factors associated with catheter-related thrombosis. Malignancy, history of thrombophilia, history of catheterization, surgery during the week before catheterization, and catheterization duration were associated with increased risks of catheter-related thrombosis. Prophylactic anticoagulation was effective for preventing and treating catheter-related thrombosis.
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