Coronavirus in pregnancy. What we know so far?

Area of Science:

• Virology
• Infectious Diseases
• Public Health

Background:

• Coronaviruses, including the novel SARS-CoV-2, primarily affect mammals and birds but can transmit to humans, causing illnesses ranging from the common cold.
• SARS-CoV-2 shares 85% sequence similarity with SARS-CoV and has resulted in over 100,000 infections and nearly 5,000 deaths globally, indicating a 4% mortality rate.
• Current understanding of SARS-CoV-2 symptoms, management, and complications is largely extrapolated from previous pandemics like SARS and MERS.

Discussion:

• Information regarding viral infections in pregnant women, specifically concerning SARS-CoV-2, is notably scarce.
• Existing data on pregnant patients infected with SARS-CoV-2 is limited, and current knowledge is often generalized from other severe acute respiratory syndrome (SARS) infections.
• The unique physiological state of pregnancy may influence viral pathogenesis and outcomes, necessitating specific research.

Key Insights:

• The SARS-CoV-2 virus presents a significant global health challenge with a considerable mortality rate.
• Knowledge gaps persist regarding the impact of SARS-CoV-2 on pregnant individuals.
• Research into SARS-CoV-2 in pregnancy is critical due to potential implications for both maternal and fetal health.

Outlook:

• Further clinical studies are essential to elucidate the specific effects of SARS-CoV-2 infection in pregnant women.
• Developing targeted management strategies and understanding potential complications for this demographic are priorities.
• Ongoing research will inform public health responses and clinical guidance for pregnant populations during the COVID-19 pandemic.