Genital Sweet's Syndrome in a patient with Acute Myelogenous Leukemia

A 71 year old male presented to the emergency room for evaluation of acute erythema, edema and pain of the penis and scrotum. There was initial concern for Fournier's gangrene, however labs were unremarkable and vital signs were stable. He did not improve with antibiotics. Biopsy results showed neutrophil infiltration consistent with Sweet's Syndrome. He was started on corticosteroids and discharged home in stable condition. In a hemodynamically stable patient not responding to antibiotic therapy, close observation is prudent until the tissue biopsy results.