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A glimpse of hope: cardiac surgery in low- and middle-income countries (LMICs)
Peter Zilla1, R Morton Bolman2, Percy Boateng3
1Christian Barnard Department for Cardiothoracic Surgery, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Insights
Millions in low- and middle-income countries (LMICs) lack access to life-saving cardiac surgery, with rheumatic heart disease (RHD) being a major cause. Expanding surgical services in LMICs faces significant challenges despite growing needs.
Area of Science:
- Cardiovascular Surgery
- Global Health Equity
- Public Health Policy
Background:
- The majority of the global population resides in low- and middle-income countries (LMICs), yet cardiac surgical needs in these regions are largely unmet.
- While high-income countries (HICs) see declining cardiac surgery demands, LMICs face a critical deficit in access to essential heart operations.
Purpose of the Study:
- To highlight the disparity in cardiac surgical access between HICs and LMICs.
- To underscore the significant burden of Rheumatic Heart Disease (RHD) as a primary driver of cardiac surgical needs in LMICs, particularly among younger populations.
- To identify the challenges hindering the expansion of cardiac surgical services in LMICs.
Main Methods:
- Comparative analysis of cardiac surgical needs and capacities in HICs versus LMICs.
- Examination of the epidemiological drivers of cardiac surgical demand in different income settings, focusing on RHD prevalence.
- Assessment of existing cardiac surgical infrastructure and service delivery models in LMICs.
Main Results:
- Rheumatic heart disease (RHD) is the predominant indication for cardiac surgery in young patients in low- and middle-income countries, significantly outweighing other conditions.
- Cardiac surgical capacity in LMICs is severely limited (0.5-481 operations/million population) compared to HICs (>1,200 operations/million).
- Despite recent efforts to establish local services in low-income countries (LICs), coverage remains below 2% of the population's needs, while middle-income countries (MICs) face growing demand and access gaps.
Conclusions:
- Urgent global health strategies are required to address the critical unmet need for cardiac surgery in LMICs.
- Overcoming challenges such as limited surgical skills, valve availability, and socioeconomic barriers is crucial for improving cardiac care access in LMICs.
- Addressing the specific needs of younger RHD patients and bridging the gap between public and private healthcare in MICs are essential for equitable cardiac surgical care.
Abstract:
Currently, more than five times more people live in low- and middle-income countries (LMICs) than in high-income countries (HICs). As such, the downward trend in cardiac surgical needs in HICs reflects only the situation of one sixth of the world population while the vast majority living in LMICs has still no or limited access to life saving heart operations. In these countries, rheumatic heart disease (RHD) still accounts for a significant proportion of cardiac surgical needs. In low- and lower-middle income countries it remains the single most common cardiovascular disease in young adult and adolescent patients in need of heart surgery outweighing other indications such as congenital cardiac defects almost 4-fold. Compared to HICs with their predominance of calcific aortic stenosis in the elderly mitral valve surgery is required in >90% of the largely young patients with RHD in low-income countries (LICs) and still in 70% of the often middle aged patients in middle-income countries (MICs). Although recent government initiatives in LICs led to the establishment of local, independent cardiac surgical services gradually replacing fly-in missions, these centers still only cover less than 2% of the needs of their populations. In MICs, cardiac surgical needs continually grow with the emergence of degenerative diseases. As such, in spite of the concomitant growth of cardiac surgical capacity, significantly less than half the estimated patients in need have access. Capacities in LICs range from 0.5 to 7 cardiac operations/million population; 100-481/million in MICs and >1,200/million in HICs such as the USA and Germany. While a new level of awareness of the scope and magnitude of the problem has begun to emerge in LICs and the establishment of local cardiac surgical capacity has given rise to a glimpse of hope, the challenges of expanding these fledgling services to a significant proportion of the population still seem insurmountable. Challenges in MICs are on the other hand the widening gap between private cardiac medicine for the affluent few and overwhelmed public services for the many and the rural urban divide with the underappreciation of the ongoing dominance of RHD in the rural and indigent population on the other. Overshadowing all LMICs is the low level of valve-repair skills associated with insufficient cardiac surgical capacity and the unavailability of suitable replacement valves which address the young age of the patients and the difficulties of anticoagulation in a socioeconomic environment distinctly different from the elderly patients of HICs.
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