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A Murine Tail Lymphedema Model
Published on: February 10, 2021
Surgical management of lymphedema: a review of current literature
Kitae E Park1, Omar Allam1, Ludmila Chandler1
1Division of Plastic and Reconstructive Surgery, Yale University School of Medicine, New Haven, CT, USA.
Abstract:
Lymphedema may be characterized by a progressive clinical course and limitations in improvement despite multi-modality treatment. In westernized countries, it most commonly presents as an undesirable complication of cancer treatment, particularly breast cancer. In the past several decades, surgical treatments for lymphedema have advanced, alongside developments in microsurgery. Lymphovenous anastomosis (LVA) and lymph node transplantation are physiological therapies that may reduce lymphedema through addressing its route cause. Ablative techniques such as liposuction and subcutaneous excision aid in resolving the accumulation of proteinaceous adipose and fibrotic tissue seen in advanced lymphedema. The goal of this review is to examine the outcomes and limitations of current surgical techniques used in lymphedema management.
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