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Light-responsive nanozymes for biosensing.

Yufeng Liu¹, Xiaoyu Wang, Hui Wei

¹Department of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing National Laboratory of Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, Jiangsu 210093, China. weihui@nju.edu.cn.

|May 19, 2020

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This review explores light-responsive nanozyme biosensors. We discuss strategies for using light to control nanozyme activity and build advanced photo-responsive biosensing systems for efficient detection.

Area of Science:

Biomedical Engineering
Nanotechnology
Analytical Chemistry

Background:

Light stimulation is crucial for modulating nanozyme activity.
Nanozyme-based biosensing systems offer high sensitivity and specificity.
Integrating light-responsiveness enhances biosensor control and efficiency.

Purpose of the Study:

To review recent advancements in light-responsive nanozyme-based biosensing systems.
To highlight strategies for constructing efficient photo-responsive nanozyme biosensors.
To discuss detection mechanisms, challenges, and future directions.

Main Methods:

Review of recent literature on light-responsive nanozymes.
Categorization of strategies based on nanozyme type (metal, carbon, MOF).

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Analysis of detection mechanisms in photo-responsive biosensors.

Main Results:

Light can effectively regulate nanozyme catalytic activity.
Various nanozyme types (metal, carbon, MOF-based) can be engineered for photo-responsiveness.
Different detection mechanisms are employed in these advanced biosensing systems.

Conclusions:

Light-responsive nanozyme biosensors represent a promising frontier in diagnostics.
Further research is needed to address current challenges and unlock future potential.
This technology holds significant promise for sensitive and controlled biomolecule detection.