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Updated: Dec 21, 2025
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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
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The bicuspid aortic valve: Still a toothy problem.
1Department of Medicine/Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Summary
Transcatheter aortic valve replacement (TAVR) is a viable option for select patients with bicuspid aortic valves, showing good mid-term results. Further large-scale trials are needed to confirm TAVR
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Cardiac Surgery
Background:
- Bicuspid aortic valve disease presents unique challenges for aortic valve replacement.
- Transcatheter aortic valve replacement (TAVR) is increasingly considered for bicuspid aortic valve patients.
- Surgical aortic valve replacement (SAVR) remains a standard treatment option.
Discussion:
- TAVR demonstrates acceptable mid-term outcomes in selected patients with bicuspid aortic stenosis.
- Patient selection is crucial for successful TAVR in this population.
- Comparing TAVR directly with SAVR in bicuspid aortic valve patients requires further investigation.
Key Insights:
- TAVR is a suitable alternative to SAVR for specific bicuspid aortic valve patients.
- Mid-term results for TAVR in bicuspid aortic stenosis are promising.
- Current evidence supports TAVR in carefully selected individuals.
Outlook:
- A large-scale, randomized clinical trial is essential to definitively establish the role of TAVR for bicuspid aortic stenosis.
- Future research should focus on long-term outcomes and comparative effectiveness.
- Optimizing patient selection criteria for TAVR in bicuspid aortic valve disease is a priority.
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