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COVID-19: An Update About the Discovery Clinical Trial.
1Formerly head of the Department of Organic Chemistry (FS), University of Mons-UMONS, 7000 Mons, Belgium.
Pharmaceuticals (Basel, Switzerland)
|May 20, 2020
Summary
Finding effective COVID-19 treatments is vital. The European Discovery project evaluated small molecules like remdesivir and hydroxychloroquine, but complete clinical data are pending.
Area of Science:
- Virology
- Infectious Diseases
- Pharmacology
Background:
- The COVID-19 pandemic necessitates urgent identification of safe and effective treatments.
- While plasma therapy is explored, small molecule antivirals represent a key therapeutic avenue.
Purpose of the Study:
- To compile and report on the clinical evaluation results of specific small molecule drugs investigated by the European Discovery project for COVID-19 treatment.
Main Methods:
- The study involved a review of recently published clinical evaluation results for selected drugs.
- Focus was placed on remdesivir, lopinavir/ritonavir combination, hydroxychloroquine, and chloroquine.
Main Results:
- Published results from the clinical evaluation of these small molecules are presented.
- The report acknowledges that complete data are still awaited, indicating ongoing research.
Conclusions:
- The European Discovery project is investigating promising small molecule candidates for COVID-19.
- Further comprehensive data are required to fully ascertain the efficacy and safety of these treatments.
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