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Biotransformation of 1,4-cineole, a monoterpene ether
Y Asakawa1, M Toyota, T Ishida
1Faculty of Pharmaceutical Science, Tokushima Bunri University, Japan.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|October 1, 1988
Abstract:
1. The metabolism of 1,4-cineole, a monoterpene ether, was studied in the rabbit. 2. Four neutral and one acidic metabolites were isolated from the urine and shown to be 9-hydroxy-1,4-cineole, 3,8-dihydroxy-1,4-cineole, 8,9-dihydroxy-1,4-cineole, 1,4-cineole-8-en-9-ol and 1,4-cineole-9-carboxylic acid.