Identification and drug susceptibility testing for nontuberculous mycobacteria
Wei-Chang Huang1, Ming-Chih Yu2, Yi-Wen Huang3
1Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, 407, Taiwan; Department of Medical Technology, Jen-Teh Junior College of Medicine, Nursing and Management, Miaoli, 350, Taiwan; Department of Life Sciences, National Chung-Hsing University, Taichung, 402, Taiwan; Department of Industrial Engineering and Enterprise Information, Tunghai University, Taichung, 407, Taiwan.
Abstract:
Great progress has recently been made in methodologies for identifying nontuberculous mycobacteria (NTM). Recommendations for drug susceptibility testing (DST) of NTM have been expanded and updated by the Clinical and Laboratory Standards Institute and are crucial in the management of NTM infections. This article summarizes the clinically relevant molecular methods used to discriminate NTM species and updates the information on DST. Furthermore, recent progress on new antimicrobials against NTM infections is reviewed.
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