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Assessment of changes in the macula and optic nerve head using optical coherence tomography in patients with
I Sánchez-Guillén1, I Almorín-Fernández-Vigo2, J I Fernández-Vigo3
1Centro Internacional de Oftalmología Avanzada, Badajoz, España; Departamento de Oftalmología, Hospital de Zafra, Zafra, Badajoz, España.
Introduction:
To assess if there are any differences in macular and papillary thickness using optical coherence tomography (OCT) in patients with attention deficit hyperactivity disorder (ADHD) compared with a control group, including if there are differences between ADHD patients with and without treatment.
Methods:
Prospective observational study including 92 eyes of 46 patients divided into 2 groups: 46 eyes of 23 patients with ADHD, and a control group of 46 eyes of 23 healthy patients. The group of patients with ADHD was subdivided into those on treatment with methylphenidate (n=28) and those not on treatment (n=18). The macular thickness, the ganglion cell complex (GCC), and the retinal nerve fibre layer (RNFL) at the papillary level were measured in 12 sectors.
Results:
A lower central macular thickness was observed in the ADHD patients than in the controls (257.4±20μm versus 267.5±20μm, P=.013), with no differences observed in the GCC (P=.566), or in the RNFL (P=.095). There were no differences in the patients with ADHD with and without treatment, as regards macular thickness and the GCC (P=.160 and P=.375 respectively), but a lower foveal thickness (P=.018) and RNFL in 5/12 sectors at the papillary level (P=.033) were observed in those without treatment.
Conclusions:
A lower macular thickness was observed in patients with ADHD than in controls. In addition, patients with ADHD without treatment had a lower thickness of the fovea and RNFL than those patients on treatment.
