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Gorham Disease Limited to the Left Upper Extremity Without Hand Involvement
Alexander S Kuczmarski1, Christopher W Myers1, Van Krueger1
1Department of Orthopaedic Surgery, Alpert Medical School of Brown University, Providence, RI.
The Journal of Hand Surgery
|May 20, 2020
Summary
This case report details a young female with Gorham disease experiencing multiple forearm fractures due to bone loss. The findings highlight the progressive nature of this rare condition in affected limbs.
Area of Science:
- Orthopedics
- Rare bone diseases
- Radiology
Background:
- Gorham disease is a rare condition characterized by massive osteolysis (bone loss).
- It can lead to pathologic fractures and skeletal deformities.
- This report focuses on a pediatric case with extensive forearm involvement.
Observation:
- A young female with known Gorham disease presented after a low-impact fall.
- Radiographs revealed massive osteolysis of the left radius, ulna, and wrist.
- The patient had a history of 8 prior fractures in the same upper extremity.
Findings:
- Pathologic fractures of the left radius and ulna occurred secondary to severe osteolysis.
- The disease appeared localized to the left upper extremity.
- The extent of bone loss significantly impacted the patient's skeletal integrity.
Implications:
- This case underscores the severe skeletal fragility associated with Gorham disease.
- Early recognition and management are crucial for preventing further fractures and deformities.
- Further research into Gorham disease pathogenesis and treatment is warranted.
Keywords:
Gorham diseaseidiopathic osteolysismassive osteolysispathologic fracturevanishing bone diseaseMore Related Videos
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