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COVID-19 in adults: test menu for hospital blood science laboratories

Paula M O'Shea1, Graham Robert Lee2, Tomás P Griffin3

  • 1Department of Clinical Biochemistry, Saolta University Health Care Group (SUHCG), Galway University Hospitals, Newcastle Road, Galway, Ireland. PaulaM.OShea@hse.ie.

Irish Journal of Medical Science
|May 20, 2020
PubMed

Insights

This study outlines a clinical blood sciences laboratory testing protocol for managing coronavirus disease 2019 (COVID-19). Regular monitoring of key blood parameters is crucial for effective patient management and prognostication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Area of Science:

  • Clinical Laboratory Science
  • Infectious Disease Diagnostics
  • Biochemistry and Hematology

Background:

  • Coronavirus disease 2019 (COVID-19) is a significant global health concern caused by SARS-CoV-2.
  • The Clinical Blood Sciences Laboratory (CBSL) is integral to patient care for COVID-19.
  • Effective laboratory support is vital for managing SARS-CoV-2 infections.

Purpose of the Study:

  • To establish a comprehensive testing protocol for CBSL in the context of COVID-19.
  • To guide the medical management of patients infected with SARS-CoV-2.
  • To standardize laboratory approaches for COVID-19 patient assessment.

Main Methods:

  • Detailed description of biochemical assays relevant to COVID-19.
  • Explanation of haematological tests for monitoring COVID-19 patients.
  • Outline of immunological investigations utilized in SARS-CoV-2 infection.

Main Results:

  • A defined test menu is provided for clinical laboratories.
  • The menu facilitates effective monitoring of COVID-19 patients.
  • The protocol aids in the management and prognostication of hospitalized COVID-19 cases.

Conclusions:

  • Rapid deterioration is a characteristic of severe COVID-19.
  • Regular laboratory testing is recommended for vigilance.
  • Monitoring the rate and trajectory of change in key parameters is essential for patient outcomes.
Abstract

Keywords:
Blood science testingCOVID-19Hospital laboratoriesMonitoring and management

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