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Lung infection caused by Rhodococcus.

D H Hart¹, M M Peel, J H Andrew

¹St Vincent's Hospital, Vic., Australia.

Australian and New Zealand Journal of Medicine

|October 1, 1988

Summary

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A rare lung infection caused by Rhodococcus rubropertinctus, mimicking tuberculosis in an immunocompetent patient, was successfully treated. The treatment involved standard anti-tuberculosis drugs and tetracycline.

Area of Science:

Microbiology
Infectious Diseases
Pulmonology

Background:

Rhodococcus rubropertinctus infections are uncommon, particularly in immunocompetent individuals.
The 'rhodochrous' complex typically causes opportunistic infections in immunocompromised hosts.
Distinguishing Rhodococcus infections from tuberculosis can be challenging clinically.

Observation:

A case of lung infection clinically resembling tuberculosis is presented.
The patient exhibited no signs of immunosuppression, which is atypical for this type of infection.
Microbiological identification revealed Rhodococcus rubropertinctus as the causative agent.

Findings:

The lung infection successfully responded to a regimen of oral anti-tuberculosis therapy.

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Rifampicin, a key component of the anti-tuberculosis treatment, was administered.

Oral tetracycline was also included in the treatment protocol and proved effective.

Implications:

This case highlights the potential for Rhodococcus rubropertinctus to cause pulmonary disease in immunocompetent individuals.
The successful treatment with standard anti-tuberculosis drugs and tetracycline offers a therapeutic guideline.
Further research may be warranted to understand the pathogenesis and optimal treatment strategies for Rhodococcus pulmonary infections.