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Regulation of cell division and malignant transformation
1Centre for Cellular & Molecular Biology, Hyderabad, India.
Bioscience Reports
|December 1, 1988
Abstract:
The problem of regulation of cell division is essentially a problem of understanding regulation of transition from the resting state of a cell to the dividing state and vice versa. In malignancy the ability to revert back to a normal resting state is impaired. A model is presented which attempts to explain the control of the above transitions through control of uptake of essential nutrients by a transport-inhibitory protein. Experimental evidence in favour of the model is given.