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Neurostimulation in neurogenic patients
F M J Martens1, K-D Sievert2,3
1Department of Urology, Radboud University Medical Center, The Netherlands.
Current Opinion in Urology
|May 20, 2020
Summary
Electrical stimulation shows promise for neurogenic lower urinary tract disease. More research is needed to evaluate treatments like sacral neuromodulation (SNM) and posterior tibial nerve stimulation (PTNS) specifically in neurogenic populations.
Area of Science:
- Urology
- Neurology
- Biomedical Engineering
Background:
- Neurogenic lower urinary tract disease (NLUTD) significantly impacts quality of life.
- Current treatment options for NLUTD are limited, especially for complex cases involving multiple organ dysfunction.
Purpose of the Study:
- To review available electrical stimulation devices for managing NLUTD.
- To highlight the potential of neuromodulation techniques in neurogenic patient populations.
Main Methods:
- Literature review of electrical stimulation modalities for lower urinary tract dysfunction.
- Analysis of studies focusing on neurogenic patients, including Brindley procedure, sacral neuromodulation (SNM), and posterior tibial nerve stimulation (PTNS).
Main Results:
- The Brindley procedure is established for specific spinal cord injury patients.
- Sacral neuromodulation (SNM) and posterior tibial nerve stimulation (PTNS) show promise but require further investigation in neurogenic cohorts.
- Existing studies often lack separate analysis or sufficient numbers of neurogenic patients.
Conclusions:
- Neuromodulation offers a potential advantage by addressing multiple organ systems (bladder and bowel) affected in neurogenic patients.
- Further dedicated research is crucial to establish the efficacy and indications of SNM and PTNS in diverse neurogenic patient groups.

