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Updated: Dec 21, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
Impact of intermittent fasting on body weight in overweight and obese individuals
Carlos Henrique Ribeiro Lima1, Iara Katrynne Fonsêca Oliveira1, Karoline de Macêdo Gonçalves Frota1
1. Universidade Federal do Piauí, Departamento de Nutrição, programa de Pós-graduação em Alimentos e Nutrição. Campus Universitário Ministro Petrônio Portela, s/n -Bloco 13- Bairro Ininga, 64049-550, Teresina - PI, Brasil.
Objective:
To verify the relationship of intermittent fasting in the bodyweight of overweight and obese individuals through a systematic literature review.
Methods:
This is a systematic review based on randomized controlled trials. The articles were consulted in the databases: Science Direct, PubMed e BVS. This review was evaluated through the PRISMA recommendation.
Results:
After the selection process, four articles were included in this review, comparing intermittent fasting (IF) with calorie restriction diet (CRD) as a control group. In 2 studies using similar protocols, there was no significant reduction in body weight of overweight or obese subjects. In the other two studies using different protocols, weight loss was significant in the IF group compared to the CRD group.
Conclusions:
Results did not provide evidence of the effect of intermittent fasting on weight loss in overweight or obese individuals.
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