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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Anger and long-term mortality and ventricular arrhythmias in patients with a first-time implantable
Susanne S Pedersen1,2, Christina Maar Andersen1, Matthew Burg3,4
1Department of Psychology, University of Southern Denmark, Campusvej 55, DK-5230 Odense, Denmark.
Insights
Higher state anger in patients with implantable cardioverter-defibrillators (ICDs) is linked to increased 7-year mortality risk. Trait anger and anger
Area of Science:
- Cardiology
- Psychology
- Behavioral Medicine
Background:
- Psychosocial factors significantly influence heart disease prognosis.
- Negative emotions in implantable cardioverter-defibrillator (ICD) patients are linked to mortality, but associations with ventricular arrhythmias (VAs) are inconsistent.
- Anger has been associated with ICD shocks, yet prospective data on anger's impact on mortality and VAs in ICD patients is lacking.
Purpose of the Study:
- To investigate the association between state and trait anger and 7-year mortality risk in first-time ICD patients.
- To examine the relationship between state and trait anger and the time to the first ventricular arrhythmia (VA) in ICD patients.
Main Methods:
- A cohort of 388 first-time ICD patients (2003-2010) completed the State-Trait Anger Scale.
- Patients were followed for 7 years to assess mortality and time to first appropriate ICD therapy.
- Statistical analyses were performed to determine the association between anger scores and clinical outcomes.
Main Results:
- State anger at the time of ICD implantation was significantly associated with increased 7-year mortality risk (HR 1.05 per point increase; P=0.015).
- Each 1-point increase in state anger score correlated with a 5% rise in mortality risk.
- No significant association was found between trait anger and mortality risk, nor between state or trait anger and time to first treated VA.
Conclusions:
- This study is the first to prospectively link state anger to long-term mortality in ICD patients.
- Anger reduction strategies, such as mindfulness or self-regulation, may be beneficial for improving outcomes in newly implanted ICD patients.
- Further research into psychological interventions for ICD patients is warranted to mitigate mortality risk.
Aims:
Psychosocial factors increase risk for incident heart disease and poor prognosis. In patients with an implantable cardioverter-defibrillator (ICD), negative emotions have been associated with increased mortality risk, although the association with ventricular arrhythmias (VAs) is less consistent. Anger has been linked to incident ICD shocks, but no prospective study has examined the association of anger (state and trait) with mortality or VAs in the ICD population. In a consecutively recruited cohort of first-time ICD patients, we examined the association of state and trait anger with 7-year mortality risk and time to first VA.
Methods And Results:
A consecutive cohort of patients implanted with a first-time ICD (n = 388; 80% men) between 2003 and 2010 completed the State-Trait Anger Scale and were followed for 7 years. Outcomes were mortality and time to first appropriate ICD therapy. State anger at the time of implant was associated with increased mortality risk in adjusted analyses, with a 1-point increase in score on the state anger measures associated with a 5% [hazard ratio 1.05; 95% confidence interval 1.01-1.09; P = 0.015] increased 7-year mortality risk. We found no statistically significant differences in mortality risk for trait anger, nor an effect for state or trait anger on time to first treated VA (all ps > 0.05).
Conclusion:
This is the first study to examine the association of state and trait anger with long-term clinical outcomes in ICD patients. Evaluating anger reduction strategies in newly implanted ICD patients, such as self-regulation or mindfulness techniques, may be warranted for reducing mortality risk.
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