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Updated: Dec 21, 2025

Computational Analysis of the Caenorhabditis elegans Germline to Study the Distribution of Nuclei, Proteins, and the Cytoskeleton
Published on: April 19, 2018
The evolution of germ-soma nuclear differentiation in eukaryotic unicells
Chao-Yin Cheng1, Eduardo Orias2, Jun-Yi Leu3
1Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.
Abstract:
In this primer, Cheng et al. outline what we know about the nature and control of differentiation of germline versus somatic nuclei in two groups of protozoa: the Ciliates and Foraminifera. This is shown to involve a remarkable variety of developmentally programmed phenomena such as genome editing mediated epigenetically by RNA, as well differential nuclear import.
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