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Updated: Dec 21, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Advances in the relationship between coronavirus infection and cardiovascular diseases
Mengmeng Zhao1, Menglong Wang1, Jishou Zhang1
1Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China; Cardiovascular Research Institute, Wuhan University, Wuhan, China; Hubei Key Laboratory of Cardiology, Wuhan, China.
Insights
Coronaviruses, including COVID-19, can worsen cardiovascular disease and cause myocardial injury, leading to poor prognosis. Understanding these links is crucial for preventing and treating coronavirus infections.
Area of Science:
- Infectious Diseases
- Cardiology
- Virology
Background:
- Seven human coronaviruses (HCoVs) are known, including SARS-CoV-2 causing COVID-19.
- Cardiovascular disease (CVD) is linked to increased incidence and severity of coronavirus infections.
- Myocardial injury from coronavirus infection is a key factor in poor patient outcomes.
Purpose of the Study:
- To review recent clinical findings on the relationship between coronaviruses and cardiovascular diseases.
- To discuss the underlying pathophysiological mechanisms involved.
- To aid in the prevention and treatment strategies for COVID-19.
Main Methods:
- Literature review of recent clinical studies.
- Analysis of pathophysiological mechanisms.
- Synthesis of current knowledge on coronavirus-CVD interactions.
Main Results:
- Coronaviruses significantly impact cardiovascular health.
- Myocardial injury is a common complication of coronavirus infections.
- CVD exacerbates coronavirus disease severity and prognosis.
Conclusions:
- There is a critical link between coronaviruses and cardiovascular diseases.
- Understanding these interactions is vital for clinical management.
- Further research can improve prevention and treatment of COVID-19 and related cardiac complications.
Abstract:
The outbreak of coronavirus disease 2019 (COVID-19) has once again aroused people's concern about coronavirus. Seven human coronaviruses (HCoVs) have been discovered so far, including HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU115, severe acute respiratory syndrome coronavirus, Middle East respiratory syndrome coronavirus and severe acute respiratory syndrome coronavirus 2. Existing studies show that the cardiovascular disease increased the incidence and severity of coronavirus infection. At the same time, myocardial injury caused by coronavirus infection is one of the main factors contributing to poor prognosis. In this review, the recent clinical findings about the relationship between coronaviruses and cardiovascular diseases and the underlying pathophysiological mechanisms are discussed. This review aimed to provide assistance for the prevention and treatment of COVID-19.
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