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Additional laboratory tests to improve on the diagnosis of antiphospholipid syndrome
1Thrombosis Research Laboratory, University of Padova, Padova, Italy.
Abstract:
Whether additional tests to improve on the diagnosis of antiphospholipid syndrome are useful is a matter of debate. New tests exploring the presence of antiphospholipid antibodies are now available and comprise subgroups of antibodies directed to β2-glycoprotein I, namely anti-Domain 1 and anti-Domain 4/5, and anti-phosphatidylserine/prothrombin antibodies. The aim of this article is to discuss in a forum with the scientific community on the possible utility of additional test for the diagnosis of antiphospholipid syndrome, especially in incomplete antiphospholipid antibody profiles.
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