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Related Experiment Video

Updated: Dec 21, 2025

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
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Decontamination of Titanium Surface Using Different Methods: An In Vitro Study.

Sifan Yan1, Min Li1, Satoshi Komasa1

  • 1Department of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1 Kuzuha-hanazono-cho, Hirakata, Osaka 573-1121, Japan.

Materials (Basel, Switzerland)
|May 21, 2020
PubMed
Summary

A new Finevo cleaning system effectively decontaminates hydrocarbon-polluted titanium dental implants. This method restores implant bioactivity, significantly enhancing rat bone marrow mesenchymal stem cell (rBMMSC) attachment and osteogenic differentiation.

Keywords:
Finevo cleaning systemTi implanthydrocarbon decontaminationplasmaultraviolet treatment

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Area of Science:

  • Biomaterials Science
  • Surface Chemistry
  • Regenerative Medicine

Background:

  • Implant contamination is a significant challenge in production and clinical use.
  • Restoring bioactivity on contaminated implant surfaces is crucial for successful osseointegration.
  • Current cleaning methods may not fully restore implant surface functionality.

Purpose of the Study:

  • To introduce and evaluate a novel implant cleaning strategy using the Finevo system.
  • To compare the efficacy of the Finevo system against Ultraviolet and Plasma treatments for decontaminating titanium disks.
  • To assess the impact of cleaning methods on the biological activity and osseointegration potential of titanium surfaces.

Main Methods:

  • Hydrocarbon contamination of titanium disks.
  • Cleaning using Finevo system, Ultraviolet (UV) treatment, and Plasma treatment.
  • Surface characterization via Scanning Electron Microscopy (SEM), X-ray Photoelectron Spectroscopy (XPS), and Scanning Probe Microscopy (SPM).
  • In vitro evaluation of rat bone marrow mesenchymal stem cells (rBMMSCs) attachment, proliferation, and osteogenic differentiation (alkaline phosphatase activity, calcium deposition, gene expression).

Main Results:

  • Finevo system cleaning resulted in titanium surfaces comparable to uncontaminated disks in SEM and XPS analyses.
  • No significant change in surface roughness was observed with Finevo cleaning via SPM.
  • rBMMSCs exhibited superior attachment and coverage on Finevo-treated disks.
  • Significantly higher alkaline phosphatase activity, calcium deposition, and osteogenesis-related gene expression in rBMMSCs on Finevo-treated disks compared to UV and Plasma treatments.

Conclusions:

  • The Finevo cleaning system effectively decontaminates hydrocarbon-contaminated titanium disks.
  • Finevo treatment restores and enhances the biological functions of titanium implant surfaces.
  • This novel strategy offers a promising approach for cleaning contaminated dental implants and promoting osseointegration.