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Clinical practice patterns in revascularization of diabetic patients with coronary heart disease: nationwide register
Hanna-Riikka Lehto1, Arto Pietilä1, Teemu J Niiranen1,2
1THL - Finnish Institute for Health and Welfare, Helsinki, Finland.
Insights
Diabetic patients with coronary heart disease were more likely to undergo coronary artery bypass grafting (CABG) than percutaneous coronary intervention (PCI), despite PCI being the dominant method overall. Diabetic patients also had more urgent CABG procedures and comorbidities.
Area of Science:
- Cardiology
- Diabetology
- Public Health
Background:
- Coronary heart disease (CHD) management differs in diabetic patients.
- Understanding revascularization trends in diabetic versus non-diabetic patients is crucial for optimizing cardiovascular care.
Purpose of the Study:
- To compare revascularization methods (PCI vs. CABG) in diabetic and non-diabetic patients with CHD.
- To analyze comorbidities and procedure urgency in these groups.
- To investigate factors influencing revascularization method choice.
Main Methods:
- Retrospective analysis of electronic health records from Finland (2000-2015).
- Inclusion of 33,018 diabetic and 106,224 non-diabetic patients undergoing first-time PCI or CABG.
- Statistical analysis to compare groups and identify predictors of revascularization method.
Main Results:
- Percutaneous coronary intervention (PCI) was the most common revascularization method overall.
- Diabetic patients were more likely to undergo coronary artery bypass grafting (CABG) than PCI (OR 1.30).
- Diabetic patients had a higher proportion of urgent CABG procedures (26.9% vs. 21.6%) and more comorbidities.
Conclusions:
- While PCI dominated, CABG was more prevalent in diabetic CHD patients compared to non-diabetic counterparts.
- Diabetic patients presented with higher urgency and more comorbidities, influencing revascularization choices.
- Patient characteristics like prior myocardial infarction and comorbidities significantly impacted CABG likelihood in diabetic individuals.
Abstract:
Aims: To compare diabetic patients with coronary heart disease (CHD) needing revascularization to corresponding non-diabetic patients in terms of revascularization methods, comorbidities and urgency of procedure. We also examined the impact of patient characteristics and comorbidities on the revascularization method.Methods: We identified all diabetic (n = 33,018) and non-diabetic (n = 106,224) patients with first-ever, percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) from electronic health records in Finland between 2000 and 2015.Results: Overall, PCI was the most common revascularization method. PCI outnumbered CABG in women and men both in diabetic and non-diabetic patients. However, diabetic patients were more likely to undergo CABG than PCI (OR 1.30; 95% CI 1.27-1.34, adjusted for age, gender, region of residence and procedure year). Moreover, 26.9% of diabetic patients' urgent procedures were CABG compared to 21.6% in non-diabetic patients (p<.001). Among diabetic patients, prior myocardial infarction was associated with increased odds of CABG, whereas female gender, atrial fibrillation, congestive heart failure, hypertension and later procedure year were associated with lower odds of CABG.Conclusions: CABG has been performed more frequently in diabetic than in non-diabetic CHD patients. Nevertheless, PCI was the dominant revascularization method over CABG both in diabetic and non-diabetic patients. KEY MESSAGESPCI was the dominant revascularization method in both diabetic and non-diabetic patients. Diabetic patients were more likely to undergo CABG than PCI when compared to non-diabetic patients (OR: 1.30; CI 1.27-1.34).Diabetic patients underwent urgent CABG procedures more often than non-diabetic patients and had more comorbidities compared to non-diabetic patients.
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