Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhancing clinically cardiovascular machine learning model for risk prediction via sample augmentation.

Frontiers in medicine·2026
Same author

Serum amino acid metabolome alteration associated with urinary metal profiles among solar greenhouse workers: Findings from a cross-sectional study.

Environmental pollution (Barking, Essex : 1987)·2026
Same author

A profile analysis of leader interpersonal emotion management strategies.

The Journal of applied psychology·2026
Same author

High-fidelity fiber longitudinal power monitoring via non-uniform sparse regularization.

Optics express·2026
Same author

Pan-cancer analysis of the upstream regulator FDX1 in cuproptosis.

Discover oncology·2026
Same author

Visual and anatomic outcomes of epiretinal membrane surgery in highly myopic eyes with varying axial lengths.

International journal of ophthalmology·2026

Related Experiment Video

Updated: Dec 21, 2025

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.3K

Microfluidics in Single-Cell Virology: Technologies and Applications.

Wu Liu1, Hongzhang He2, Si-Yang Zheng3

  • 1Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

Trends in Biotechnology
|May 21, 2020
PubMed
Summary

Single-cell microfluidics offers powerful new ways to study viruses and how they infect cells. This technology provides unprecedented insights into virus-host interactions, aiding antiviral drug development.

Keywords:
heterogeneitymicrofluidicssingle-cell analysistranscriptomic analysisviral infection dynamicsvirology

More Related Videos

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform
07:15

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform

Published on: May 18, 2021

3.4K
Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation
09:50

Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation

Published on: October 27, 2019

7.4K

Related Experiment Videos

Last Updated: Dec 21, 2025

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.3K
Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform
07:15

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform

Published on: May 18, 2021

3.4K
Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation
09:50

Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation

Published on: October 27, 2019

7.4K

Area of Science:

  • Biophysics
  • Virology
  • Biotechnology

Background:

  • Microfluidics enables single-cell analysis.
  • Single-cell microfluidics is a recent advancement in virology (last 5 years).
  • Population-based studies have limitations in understanding virus-host dynamics.

Purpose of the Study:

  • To highlight the utility of single-cell microfluidics in virology.
  • To discuss its application in studying viral pathogenesis.
  • To emphasize its role in developing antiviral therapeutics.

Main Methods:

  • Microwell-based microfluidic devices
  • Microvalve-based microfluidic devices
  • Droplet-based microfluidic systems

Main Results:

  • Enables tracking of viral infection dynamics at the single-cell level.
  • Facilitates identification of specific cell subpopulations and phenotypes.
  • Supports high-throughput screening for antiviral agents.

Conclusions:

  • Single-cell microfluidics provides unprecedented insights into virus-host interactions.
  • This approach is crucial for elucidating viral pathogenesis mechanisms.
  • It opens new avenues for the development of novel antiviral therapeutics.