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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Fast T2 mapping using multi-echo spin-echo MRI: A linear order approach.

Yaghoub Fatemi1, Habibollah Danyali1, Mohammad Sadegh Helfroush1

  • 1Department of Electrical and Electronics Engineering, Shiraz University of Technology, Shiraz, Iran.

Magnetic Resonance in Medicine
|May 21, 2020
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Summary
This summary is machine-generated.

Fast Analysis of Multi-Echo Spin-Echo (FAMESE) accelerates T2 mapping by reducing search space complexity. This novel method provides accurate and reliable T2 measurements, overcoming limitations of conventional techniques.

Keywords:
T2 relaxation timeextended phase graphindirect echoesmagnetic resonance imagingstimulated echoes

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Area of Science:

  • Magnetic Resonance Imaging
  • Biomedical Engineering
  • Quantitative Imaging

Background:

  • Multi-echo spin-echo sequences are standard for T2 mapping.
  • Conventional methods overestimate T2 due to stimulated and indirect echoes.
  • Accelerated T2 mapping is crucial for clinical applications.

Purpose of the Study:

  • Introduce Fast Analysis of Multi-Echo Spin-Echo (FAMESE) as a novel T2 mapping approach.
  • Reduce the complexity of the search space for accelerated T2 measurement.
  • Improve the accuracy and efficiency of T2 mapping.

Main Methods:

  • Developed FAMESE based on mathematical analysis of Bloch equations, reducing search space to one dimension.
  • Validated FAMESE in phantom and human brain studies.
  • Assessed agreement using Bland-Altman plots and reliability using intraclass correlation coefficients.

Main Results:

  • FAMESE demonstrated accelerated and SNR-resistant T2 maps in phantoms and humans.
  • Excellent agreement was observed between FAMESE and single-echo spin-echo T2 values.
  • High intraclass correlation coefficients (0.9998 for phantom, 0.9860-0.9942 for humans) indicate excellent reliability.

Conclusions:

  • FAMESE offers a promising solution for rapid T2 mapping.
  • The method achieves clinically feasible scan times.
  • FAMESE is a strong candidate for accelerated quantitative T2 imaging.