Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antiepileptic Drugs: Potassium Channel Activators01:20

Antiepileptic Drugs: Potassium Channel Activators

524
Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
524
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

791
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
791
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

981
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
981
Antibiotic Selection00:57

Antibiotic Selection

59.2K
Overview
59.2K
Antiepileptic Drugs: GABAergic Pathway Potentiators01:18

Antiepileptic Drugs: GABAergic Pathway Potentiators

1.1K
γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
1.1K
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

204
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
204

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Biological and Psychological Profiles of Hospital Healthcare Professionals During a Stressful Wartime.

Journal of general internal medicine·2026
Same author

When the usual is unusual-Foreign body aspiration pneumonia.

The American journal of medicine·2026
Same author

Life-threatening Haemoptysis in a patient with chronic Ulcerative Colitis.

QJM : monthly journal of the Association of Physicians·2026
Same author

Opportunistic Diagnosis of Osteoporosis through CT Pulmonary Angiography for Suspected Pulmonary Embolism.

QJM : monthly journal of the Association of Physicians·2026
Same author

Ecchymosis-a neglected sign of necrotizing fasciitis.

QJM : monthly journal of the Association of Physicians·2025
Same author

Unconsciousness, Dyspnea, and Miosis -Organophosphate poisoning.

The American journal of medicine·2025
Same journal

[Tennis Elbow Among Players].

Harefuah·2026
Same journal

[Internal Medicine - My Mission].

Harefuah·2026
Same journal

[Treatment of Morbid Obesity in Israel: GLP-1 Agonists Versus Bariatric Surgery - Clinical and Economic Aspects].

Harefuah·2026
Same journal

[Baby steps: Post-operative Treatment Recommendations for Pediatric Tracheostomy in Israel].

Harefuah·2026
Same journal

[Mastoiditis Caused by Fusobacterium Necrophorum: an Unusual Pathogen in a Well-Known Disease].

Harefuah·2026
Same journal

[Cochlear Implantation in Single-Sided Deafness - Six Years of Follow-Up from Diagnosis and Consistent Use, Through Dedicated and Creative Auditory Learning, to the Development of Bilateral Central Processing Abilities].

Harefuah·2026
See all related articles

Related Experiment Video

Updated: Dec 21, 2025

Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis
08:20

Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis

Published on: June 2, 2022

3.7K

[ANTIBIOTIC-ASSOCIATED ENCEPHALOPATHY].

Ina Dubin1, Elizabeth Nissim1, Amichai Schattner1,2

  • 1Department of Medicine A, Laniado Hospital, Sanz Medical Center, Netanya.

Harefuah
|May 21, 2020
PubMed
Summary
This summary is machine-generated.

Antibiotic-associated encephalopathy (AAE) is a rare adverse drug event linked to antibiotic use. Promptly stopping the causative antibiotic typically resolves symptoms within days.

More Related Videos

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

4.3K
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.0K

Related Experiment Videos

Last Updated: Dec 21, 2025

Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis
08:20

Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis

Published on: June 2, 2022

3.7K
Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

4.3K
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.0K

Area of Science:

  • Neurology
  • Pharmacology
  • Toxicology

Background:

  • Antibiotic-associated encephalopathy (AAE) is an uncommon adverse drug event associated with intravenous antibiotic therapy.
  • Most antibiotic classes can trigger AAE, with beta-lactams potentially affecting GABA(A) receptors and neurotransmission.
  • Risk factors include renal impairment, high drug doses, and pre-existing brain conditions.

Purpose of the Study:

  • To report a typical case of antibiotic-associated encephalopathy (AAE).
  • To review the existing literature on AAE, including its pathogenesis, clinical presentation, diagnosis, and management.

Main Methods:

  • Case report presentation.
  • Comprehensive literature review of antibiotic-associated encephalopathy.

Main Results:

  • AAE presents with diverse neurological symptoms like altered consciousness, agitation, seizures, and cerebellar signs, often within the first week of antibiotic treatment.
  • EEG may show nonspecific triphasic waves; neuroimaging and laboratory tests are typically unrevealing.
  • Discontinuation of the implicated antibiotic leads to a median recovery time of 5 days.

Conclusions:

  • Increased clinical awareness of AAE is crucial for timely diagnosis and management.
  • The syndrome may become more prevalent with the expanding use of antibiotics.