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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
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Case Report: A Polymicrobial Vision-Threatening Eye Infection Associated with Polysubstance Abuse

Venkata Satish Pendela1, Pujitha Kudaravalli2, Mamta Chhabria1

  • 11Rochester Regional Health, Rochester, New York.

The American Journal of Tropical Medicine and Hygiene
|May 21, 2020
PubMed

Insights

This study identifies Kingella negevensis as a cause of microbial keratitis, a rare bacterial eye infection. This finding is significant as it

Area of Science:

  • Ophthalmology
  • Microbiology
  • Infectious Diseases

Background:

  • Microbial keratitis and endophthalmitis are serious eye infections that can be challenging to diagnose.
  • Identifying the causative organism is crucial for effective treatment and preventing vision loss.

Observation:

  • A patient presented with symptoms suggestive of both microbial keratitis and endophthalmitis.
  • Corneal scrapings revealed multiple organisms, including a previously uncultivable Gram-negative rod.

Findings:

  • The uncultivable Gram-negative rod was identified as Kingella negevensis.
  • This is the first reported case of Kingella negevensis causing microbial keratitis.

Implications:

  • This expands the known spectrum of ocular infections caused by Kingella negevensis.
  • Further research into the epidemiology and pathogenicity of Kingella negevensis is warranted.

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