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Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
Yan Chen1, Yao Lu1, Robert J Lee2
1School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
International Journal of Nanomedicine
|May 21, 2020
Summary
Curcumin, a natural compound, faces challenges in medical use due to poor solubility and stability. Nano encapsulation offers a promising solution to enhance curcumin
Area of Science:
- Pharmacology and Nanotechnology
- Natural Product Chemistry
Background:
- Curcumin, derived from turmeric, possesses diverse pharmacological properties including anti-inflammatory, anti-bacterial, and anti-cancer effects.
- Therapeutic use of curcumin is hindered by poor aqueous solubility, instability in biological fluids, and rapid metabolism.
- Nanodelivery systems present a viable strategy to overcome curcumin's limitations, enhancing its bioavailability and efficacy.
Purpose of the Study:
- To review recent advancements in nano-encapsulated curcumin formulations.
- To explore the potential of nano-encapsulated curcumin in various biomedical applications.
Main Methods:
- Literature review focusing on nanodelivery systems for curcumin.
- Analysis of studies investigating the improved properties and therapeutic effects of nano-encapsulated curcumin.
Main Results:
- Nano encapsulation significantly improves curcumin's solubility and stability.
- Nanoparticle formulations enhance curcumin's biocompatibility and therapeutic outcomes.
- Various nano delivery systems are being developed for curcumin, showing promise for biomedical applications.
Conclusions:
- Nano encapsulation is a key strategy to unlock the full therapeutic potential of curcumin.
- Further research into nano-encapsulated curcumin holds significant promise for future medical treatments.
