Related Experiment Video
Updated: Dec 21, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Blount Disease and Obstructive Sleep Apnea: An Under-recognized Association?
Achraf Jardaly1,2, Gerald McGwin2,3, Shawn R Gilbert2
1Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Insights
Children with Blount disease have a high prevalence of obstructive sleep apnea (OSA), leading to increased surgical complications. Early diagnosis and preoperative planning are crucial for managing OSA in these patients.
Area of Science:
- Pediatric Orthopedics
- Sleep Medicine
- Anesthesiology
Background:
- Obesity is a significant risk factor for both Blount disease and obstructive sleep apnea (OSA).
- Obesity and OSA can increase anesthetic and postoperative complication risks in children.
- Children with Blount disease may have co-occurring OSA, necessitating perioperative risk assessment.
Purpose of the Study:
- To determine the prevalence of OSA in children undergoing surgery for Blount disease.
- To identify perioperative complications associated with Blount disease and OSA.
- To evaluate the impact of OSA on surgical outcomes in pediatric Blount disease patients.
Main Methods:
- Retrospective review of single-institution records and analysis of the Kids' Inpatient Database.
- Inclusion criteria: patients under 18 years old undergoing corrective surgery for Blount disease.
- Study design: Level III-case-control study.
Main Results:
- Institutional review found a 23% OSA prevalence in surgically treated Blount disease patients (all obese).
- National database (Kids' Inpatient Database) showed 3% OSA diagnosis in 1059 Blount disease cases.
- Overall, 4.4% of Blount children experienced complications, increasing hospitalization by 4.3 days and charges by 39%.
Conclusions:
- A low diagnosed OSA prevalence in national data may indicate underdiagnosis in children with Blount disease.
- Untreated OSA significantly increases surgical morbidity in pediatric Blount disease patients.
- Preoperative screening and planning are essential to mitigate OSA-related complications.
Background:
Obesity is strongly associated with both Blount disease and obstructive sleep apnea (OSA). Obesity increases risks for anesthetic and postoperative complications, and OSA can further exacerbate these risks. Since children with Blount disease might have both conditions, we sought to determine the perioperative complications and the prevalence of OSA among these children.
Methods:
Patients younger than 18 years undergoing corrective surgery for Blount disease were identified from 2 sources as follows: a retrospective review of records at a single institution and querying of the Kids' Inpatient Database, a nationally representative database.
Results:
At our institution, the prevalence of OSA among patients surgically treated for Blount disease was 23% (42/184). Blount patients were obese (100%), and predominately African American (89%), and male (68%). Patients were treated for OSA before surgery, and 2 patients (1%) had postoperative hypoxemia. In contrast, of 1059 cases of Blount disease from the Kids' Inpatient Database, 3% were diagnosed with OSA. In total, 4.4% of all the Blount children experienced complications, including hypoxemia, respiratory insufficiency, atelectasis, and arrhythmias. Complications were associated with 4.3 additional days of hospitalization (P<0.0001) and 39% additional hospital charges (P=0.002).
Conclusions:
Data from the national database showed a low rate of OSA prevalence but high respiratory and OSA-associated complications, perhaps indicating that OSA may be underdiagnosed in children with Blount disease. Affected patients, especially ones with untreated OSA, sustain increased surgical morbidity. A high index of suspicion and preoperative planning helps alleviate the burden of OSA among these patients.
Level Of Evidence:
Level III-case-control study.
More Related Videos
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Other Pulmonary Disorders
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

