Related Experiment Video

Updated: Dec 21, 2025

The Isolation, Differentiation, and Quantification of Human Antibody-secreting B Cells from Blood: ELISpot as a Functional Readout of Humoral Immunity
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T-bet+ Memory B Cells Stay in Place.

Sarah F Andrews1, Susan Moir2

  • 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Immunity
|May 21, 2020
PubMed
Summary

Memory B cells expressing T-bet aid protective immunity after influenza infection. These T-bet+ memory B cells primarily reside in the spleen, showing limited movement to other tissues.

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