Feasibility of pulmonary MRI for nodule detection in comparison to computed tomography

To assess the feasibility of various magnetic resonance imaging (MRI) sequences for the detection of pulmonary nodules by comparing the detection rate of computed tomography (CT).

Forty-two patients with pulmonary nodules detected by multi-slice CT (MSCT) were prospectively enrolled in the present study between November 2016 and February 2017. Chest MRI was acquired within 24 h of CT. The MRI protocol included free-breathing radial VIBE (r-VIBE) and a conventional breathhold T1-weighted VIBE (C-VIBE) were analyzed by two independent radiologists. Both detection and morphology results of each MRI image were recorded. Subjective image evaluation in terms of overall nodule morphology on the MRI images was carried out using the 4-point scoring criteria. The MRI results were compared with those from CT, with the results of MSCT serving as the reference standard.

Two hundred and fifty-eight solid pulmonary nodules in 42 patients were detected by CT. The r-VIBE correctly detected 94% of the pulmonary nodules as compared with CT. The detection rate increased to 100% for lesions ≥6 mm. The C-VIBE had a lower overall detection rate (64.3%) of pulmonary nodules. The difference in the subjective image evaluation scores between the two sequences was statistically significant (p < 0.001).

Significantly increased detection rates were obtained with free-breathing r-VIBE as compared with C-VIBE for the detection of pulmonary nodules and also provided more information when evaluating the nodules as compared with C-VIBE.